gentoo auto-resync : 14:01:2023 - 17:52:11

10 files changed, 57 insertions, 57 deletions

diff --git a/metadata/md5-cache/sci-biology/HTSeq-2.0.2 b/metadata/md5-cache/sci-biology/HTSeq-2.0.2
index 02137392688e..97f6590ba7b5 100644
--- a/metadata/md5-cache/sci-biology/HTSeq-2.0.2
+++ b/metadata/md5-cache/sci-biology/HTSeq-2.0.2
@@ -1,17 +1,17 @@
-BDEPEND=>=dev-lang/swig-3.0.8 dev-python/cython[python_targets_python3_8(-)?,python_targets_python3_9(-)?,python_targets_python3_10(-)?] test? ( dev-python/numpy[python_targets_python3_8(-)?,python_targets_python3_9(-)?,python_targets_python3_10(-)?] sci-biology/pysam[python_targets_python3_8(-)?,python_targets_python3_9(-)?,python_targets_python3_10(-)?] >=dev-python/pytest-7.1.3[python_targets_python3_8(-)?,python_targets_python3_9(-)?,python_targets_python3_10(-)?] ) python_targets_python3_8? ( >=dev-lang/python-3.8.16:3.8 ) python_targets_python3_9? ( >=dev-lang/python-3.9.16:3.9 ) python_targets_python3_10? ( >=dev-lang/python-3.10.9:3.10 ) >=dev-python/setuptools-65.5.1[python_targets_python3_8(-)?,python_targets_python3_9(-)?,python_targets_python3_10(-)?]
+BDEPEND=>=dev-lang/swig-3.0.8 dev-python/cython[python_targets_python3_9(-)?,python_targets_python3_10(-)?] test? ( dev-python/numpy[python_targets_python3_9(-)?,python_targets_python3_10(-)?] sci-biology/pysam[python_targets_python3_9(-)?,python_targets_python3_10(-)?] >=dev-python/pytest-7.1.3[python_targets_python3_9(-)?,python_targets_python3_10(-)?] ) python_targets_python3_9? ( >=dev-lang/python-3.9.16:3.9 ) python_targets_python3_10? ( >=dev-lang/python-3.10.9:3.10 ) >=dev-python/setuptools-65.5.1[python_targets_python3_9(-)?,python_targets_python3_10(-)?]
 DEFINED_PHASES=compile configure install prepare test
-DEPEND=dev-python/numpy[python_targets_python3_8(-)?,python_targets_python3_9(-)?,python_targets_python3_10(-)?] sci-biology/pysam[python_targets_python3_8(-)?,python_targets_python3_9(-)?,python_targets_python3_10(-)?] test? ( dev-python/matplotlib[python_targets_python3_8(-)?,python_targets_python3_9(-)?,python_targets_python3_10(-)?] dev-python/pandas[python_targets_python3_8(-)?,python_targets_python3_9(-)?,python_targets_python3_10(-)?] dev-python/scipy[python_targets_python3_8(-)?,python_targets_python3_9(-)?,python_targets_python3_10(-)?] )
+DEPEND=dev-python/numpy[python_targets_python3_9(-)?,python_targets_python3_10(-)?] sci-biology/pysam[python_targets_python3_9(-)?,python_targets_python3_10(-)?] test? ( dev-python/matplotlib[python_targets_python3_9(-)?,python_targets_python3_10(-)?] dev-python/pandas[python_targets_python3_9(-)?,python_targets_python3_10(-)?] dev-python/scipy[python_targets_python3_9(-)?,python_targets_python3_10(-)?] )
 DESCRIPTION=Python support for SAM/BAM/Bowtie/FASTA/Q/GFF/GTF files
 EAPI=8
 HOMEPAGE=https://htseq.readthedocs.io/
 INHERIT=distutils-r1 flag-o-matic
-IUSE=test test python_targets_python3_8 python_targets_python3_9 python_targets_python3_10
+IUSE=test test python_targets_python3_9 python_targets_python3_10
 KEYWORDS=~amd64
 LICENSE=GPL-3+
-RDEPEND=dev-python/numpy[python_targets_python3_8(-)?,python_targets_python3_9(-)?,python_targets_python3_10(-)?] sci-biology/pysam[python_targets_python3_8(-)?,python_targets_python3_9(-)?,python_targets_python3_10(-)?] python_targets_python3_8? ( >=dev-lang/python-3.8.16:3.8 ) python_targets_python3_9? ( >=dev-lang/python-3.9.16:3.9 ) python_targets_python3_10? ( >=dev-lang/python-3.10.9:3.10 )
-REQUIRED_USE=|| ( python_targets_python3_8 python_targets_python3_9 python_targets_python3_10 )
+RDEPEND=dev-python/numpy[python_targets_python3_9(-)?,python_targets_python3_10(-)?] sci-biology/pysam[python_targets_python3_9(-)?,python_targets_python3_10(-)?] python_targets_python3_9? ( >=dev-lang/python-3.9.16:3.9 ) python_targets_python3_10? ( >=dev-lang/python-3.10.9:3.10 )
+REQUIRED_USE=|| ( python_targets_python3_9 python_targets_python3_10 )
 RESTRICT=!test? ( test ) !test? ( test )
 SLOT=0
 SRC_URI=https://github.com/htseq/htseq/archive/release_2.0.2.tar.gz -> HTSeq-2.0.2.gh.tar.gz
-_eclasses_=distutils-r1	dcd5f48510105eb95e550ab968147365	flag-o-matic	69394e25812406faa1f90edaf4969395	multibuild	bddcb51b74f4a76724ff7cf8e7388869	multilib	5ca4e49abed8e3a2f7b56920eadee157	multiprocessing	b4e253ab22cef7b1085e9b67c7a3b730	ninja-utils	38c85b725d0467e51954ea921b6c104b	out-of-source-utils	1a9007554652a6e627edbccb3c25a439	python-r1	666be58f658d6b32affe30f80e39a49e	python-utils-r1	7870d60e8b98856ef02d33397fd5ec0f	toolchain-funcs	ec8bbc28394c7305b43ea07164bd8f5f
-_md5_=eaf0038e987d5268b687db2978b9cf87
+_eclasses_=distutils-r1	dcd5f48510105eb95e550ab968147365	flag-o-matic	69394e25812406faa1f90edaf4969395	multibuild	bddcb51b74f4a76724ff7cf8e7388869	multilib	5ca4e49abed8e3a2f7b56920eadee157	multiprocessing	b4e253ab22cef7b1085e9b67c7a3b730	ninja-utils	38c85b725d0467e51954ea921b6c104b	out-of-source-utils	1a9007554652a6e627edbccb3c25a439	python-r1	666be58f658d6b32affe30f80e39a49e	python-utils-r1	a1a985ddd8795a8634b4b7f820b93143	toolchain-funcs	ec8bbc28394c7305b43ea07164bd8f5f
+_md5_=a4190a44788cf7ade175eecc1b463758
diff --git a/metadata/md5-cache/sci-biology/HTSeq-9999 b/metadata/md5-cache/sci-biology/HTSeq-9999
index aa244bf6661b..06d1be51cdef 100644
--- a/metadata/md5-cache/sci-biology/HTSeq-9999
+++ b/metadata/md5-cache/sci-biology/HTSeq-9999
@@ -1,16 +1,16 @@
-BDEPEND=>=dev-lang/swig-3.0.8 dev-python/cython[python_targets_python3_8(-)?,python_targets_python3_9(-)?,python_targets_python3_10(-)?] test? ( dev-python/numpy[python_targets_python3_8(-)?,python_targets_python3_9(-)?,python_targets_python3_10(-)?] sci-biology/pysam[python_targets_python3_8(-)?,python_targets_python3_9(-)?,python_targets_python3_10(-)?] >=dev-python/pytest-7.1.3[python_targets_python3_8(-)?,python_targets_python3_9(-)?,python_targets_python3_10(-)?] ) python_targets_python3_8? ( >=dev-lang/python-3.8.16:3.8 ) python_targets_python3_9? ( >=dev-lang/python-3.9.16:3.9 ) python_targets_python3_10? ( >=dev-lang/python-3.10.9:3.10 ) >=dev-python/setuptools-65.5.1[python_targets_python3_8(-)?,python_targets_python3_9(-)?,python_targets_python3_10(-)?] >=dev-vcs/git-1.8.2.1[curl]
+BDEPEND=>=dev-lang/swig-3.0.8 dev-python/cython[python_targets_python3_9(-)?,python_targets_python3_10(-)?] test? ( dev-python/numpy[python_targets_python3_9(-)?,python_targets_python3_10(-)?] sci-biology/pysam[python_targets_python3_9(-)?,python_targets_python3_10(-)?] >=dev-python/pytest-7.1.3[python_targets_python3_9(-)?,python_targets_python3_10(-)?] ) python_targets_python3_9? ( >=dev-lang/python-3.9.16:3.9 ) python_targets_python3_10? ( >=dev-lang/python-3.10.9:3.10 ) >=dev-python/setuptools-65.5.1[python_targets_python3_9(-)?,python_targets_python3_10(-)?] >=dev-vcs/git-1.8.2.1[curl]
 DEFINED_PHASES=compile configure install prepare test unpack
-DEPEND=dev-python/numpy[python_targets_python3_8(-)?,python_targets_python3_9(-)?,python_targets_python3_10(-)?] sci-biology/pysam[python_targets_python3_8(-)?,python_targets_python3_9(-)?,python_targets_python3_10(-)?] test? ( dev-python/matplotlib[python_targets_python3_8(-)?,python_targets_python3_9(-)?,python_targets_python3_10(-)?] dev-python/pandas[python_targets_python3_8(-)?,python_targets_python3_9(-)?,python_targets_python3_10(-)?] dev-python/scipy[python_targets_python3_8(-)?,python_targets_python3_9(-)?,python_targets_python3_10(-)?] )
+DEPEND=dev-python/numpy[python_targets_python3_9(-)?,python_targets_python3_10(-)?] sci-biology/pysam[python_targets_python3_9(-)?,python_targets_python3_10(-)?] test? ( dev-python/matplotlib[python_targets_python3_9(-)?,python_targets_python3_10(-)?] dev-python/pandas[python_targets_python3_9(-)?,python_targets_python3_10(-)?] dev-python/scipy[python_targets_python3_9(-)?,python_targets_python3_10(-)?] )
 DESCRIPTION=Python support for SAM/BAM/Bowtie/FASTA/Q/GFF/GTF files
 EAPI=8
 HOMEPAGE=https://htseq.readthedocs.io/
 INHERIT=distutils-r1 flag-o-matic git-r3
-IUSE=test test python_targets_python3_8 python_targets_python3_9 python_targets_python3_10
+IUSE=test test python_targets_python3_9 python_targets_python3_10
 LICENSE=GPL-3+
 PROPERTIES=live
-RDEPEND=dev-python/numpy[python_targets_python3_8(-)?,python_targets_python3_9(-)?,python_targets_python3_10(-)?] sci-biology/pysam[python_targets_python3_8(-)?,python_targets_python3_9(-)?,python_targets_python3_10(-)?] python_targets_python3_8? ( >=dev-lang/python-3.8.16:3.8 ) python_targets_python3_9? ( >=dev-lang/python-3.9.16:3.9 ) python_targets_python3_10? ( >=dev-lang/python-3.10.9:3.10 )
-REQUIRED_USE=|| ( python_targets_python3_8 python_targets_python3_9 python_targets_python3_10 )
+RDEPEND=dev-python/numpy[python_targets_python3_9(-)?,python_targets_python3_10(-)?] sci-biology/pysam[python_targets_python3_9(-)?,python_targets_python3_10(-)?] python_targets_python3_9? ( >=dev-lang/python-3.9.16:3.9 ) python_targets_python3_10? ( >=dev-lang/python-3.10.9:3.10 )
+REQUIRED_USE=|| ( python_targets_python3_9 python_targets_python3_10 )
 RESTRICT=!test? ( test ) !test? ( test )
 SLOT=0
-_eclasses_=distutils-r1	dcd5f48510105eb95e550ab968147365	flag-o-matic	69394e25812406faa1f90edaf4969395	git-r3	2347f8fe2d392b2a091191f94be37e6f	multibuild	bddcb51b74f4a76724ff7cf8e7388869	multilib	5ca4e49abed8e3a2f7b56920eadee157	multiprocessing	b4e253ab22cef7b1085e9b67c7a3b730	ninja-utils	38c85b725d0467e51954ea921b6c104b	out-of-source-utils	1a9007554652a6e627edbccb3c25a439	python-r1	666be58f658d6b32affe30f80e39a49e	python-utils-r1	7870d60e8b98856ef02d33397fd5ec0f	toolchain-funcs	ec8bbc28394c7305b43ea07164bd8f5f
-_md5_=eaf0038e987d5268b687db2978b9cf87
+_eclasses_=distutils-r1	dcd5f48510105eb95e550ab968147365	flag-o-matic	69394e25812406faa1f90edaf4969395	git-r3	2347f8fe2d392b2a091191f94be37e6f	multibuild	bddcb51b74f4a76724ff7cf8e7388869	multilib	5ca4e49abed8e3a2f7b56920eadee157	multiprocessing	b4e253ab22cef7b1085e9b67c7a3b730	ninja-utils	38c85b725d0467e51954ea921b6c104b	out-of-source-utils	1a9007554652a6e627edbccb3c25a439	python-r1	666be58f658d6b32affe30f80e39a49e	python-utils-r1	a1a985ddd8795a8634b4b7f820b93143	toolchain-funcs	ec8bbc28394c7305b43ea07164bd8f5f
+_md5_=a4190a44788cf7ade175eecc1b463758
diff --git a/metadata/md5-cache/sci-biology/Manifest.gz b/metadata/md5-cache/sci-biology/Manifest.gz
index fc7ad971c97f..1ab32e93ae0f 100644
--- a/metadata/md5-cache/sci-biology/Manifest.gz
+++ b/metadata/md5-cache/sci-biology/Manifest.gz
diff --git a/metadata/md5-cache/sci-biology/bcftools-1.15.1 b/metadata/md5-cache/sci-biology/bcftools-1.15.1
index b74ce72c01bd..f2b202a77bea 100644
--- a/metadata/md5-cache/sci-biology/bcftools-1.15.1
+++ b/metadata/md5-cache/sci-biology/bcftools-1.15.1
@@ -1,16 +1,16 @@
-BDEPEND=python_single_target_python3_8? ( >=dev-lang/python-3.8.16:3.8 ) python_single_target_python3_9? ( >=dev-lang/python-3.9.16:3.9 ) python_single_target_python3_10? ( >=dev-lang/python-3.10.9:3.10 )
+BDEPEND=python_single_target_python3_9? ( >=dev-lang/python-3.9.16:3.9 ) python_single_target_python3_10? ( >=dev-lang/python-3.10.9:3.10 )
 DEFINED_PHASES=configure prepare setup
-DEPEND=dev-lang/perl python_single_target_python3_8? ( dev-python/matplotlib[python_targets_python3_8(-)] ) python_single_target_python3_9? ( dev-python/matplotlib[python_targets_python3_9(-)] ) python_single_target_python3_10? ( dev-python/matplotlib[python_targets_python3_10(-)] ) =sci-libs/htslib-1.15.1*:= sys-libs/zlib python_single_target_python3_8? ( >=dev-lang/python-3.8.16:3.8 ) python_single_target_python3_9? ( >=dev-lang/python-3.9.16:3.9 ) python_single_target_python3_10? ( >=dev-lang/python-3.10.9:3.10 )
+DEPEND=dev-lang/perl python_single_target_python3_9? ( dev-python/matplotlib[python_targets_python3_9(-)] ) python_single_target_python3_10? ( dev-python/matplotlib[python_targets_python3_10(-)] ) =sci-libs/htslib-1.15.1*:= sys-libs/zlib python_single_target_python3_9? ( >=dev-lang/python-3.9.16:3.9 ) python_single_target_python3_10? ( >=dev-lang/python-3.10.9:3.10 )
 DESCRIPTION=Utilities for variant calling and manipulating VCF and BCF files
 EAPI=8
 HOMEPAGE=http://www.htslib.org
 INHERIT=python-single-r1
-IUSE=python_single_target_python3_8 python_single_target_python3_9 python_single_target_python3_10
+IUSE=python_single_target_python3_9 python_single_target_python3_10
 KEYWORDS=~amd64 ~x86
 LICENSE=MIT
-RDEPEND=dev-lang/perl python_single_target_python3_8? ( dev-python/matplotlib[python_targets_python3_8(-)] ) python_single_target_python3_9? ( dev-python/matplotlib[python_targets_python3_9(-)] ) python_single_target_python3_10? ( dev-python/matplotlib[python_targets_python3_10(-)] ) =sci-libs/htslib-1.15.1*:= sys-libs/zlib python_single_target_python3_8? ( >=dev-lang/python-3.8.16:3.8 ) python_single_target_python3_9? ( >=dev-lang/python-3.9.16:3.9 ) python_single_target_python3_10? ( >=dev-lang/python-3.10.9:3.10 )
-REQUIRED_USE=^^ ( python_single_target_python3_8 python_single_target_python3_9 python_single_target_python3_10 )
+RDEPEND=dev-lang/perl python_single_target_python3_9? ( dev-python/matplotlib[python_targets_python3_9(-)] ) python_single_target_python3_10? ( dev-python/matplotlib[python_targets_python3_10(-)] ) =sci-libs/htslib-1.15.1*:= sys-libs/zlib python_single_target_python3_9? ( >=dev-lang/python-3.9.16:3.9 ) python_single_target_python3_10? ( >=dev-lang/python-3.10.9:3.10 )
+REQUIRED_USE=^^ ( python_single_target_python3_9 python_single_target_python3_10 )
 SLOT=0
 SRC_URI=https://github.com/samtools/bcftools/releases/download/1.15.1/bcftools-1.15.1.tar.bz2
-_eclasses_=multilib	5ca4e49abed8e3a2f7b56920eadee157	multiprocessing	b4e253ab22cef7b1085e9b67c7a3b730	python-single-r1	75118e916668a74c660a13b0ecb22562	python-utils-r1	7870d60e8b98856ef02d33397fd5ec0f	toolchain-funcs	ec8bbc28394c7305b43ea07164bd8f5f
-_md5_=a991b200539f7c26af7f584fe62e90f5
+_eclasses_=multilib	5ca4e49abed8e3a2f7b56920eadee157	multiprocessing	b4e253ab22cef7b1085e9b67c7a3b730	python-single-r1	75118e916668a74c660a13b0ecb22562	python-utils-r1	a1a985ddd8795a8634b4b7f820b93143	toolchain-funcs	ec8bbc28394c7305b43ea07164bd8f5f
+_md5_=7742e2f0c1176dfee3d3c8236b98c037
diff --git a/metadata/md5-cache/sci-biology/bcftools-1.16 b/metadata/md5-cache/sci-biology/bcftools-1.16
index f5a4fbd6387e..183890e0c40c 100644
--- a/metadata/md5-cache/sci-biology/bcftools-1.16
+++ b/metadata/md5-cache/sci-biology/bcftools-1.16
@@ -1,16 +1,16 @@
-BDEPEND=python_single_target_python3_8? ( >=dev-lang/python-3.8.16:3.8 ) python_single_target_python3_9? ( >=dev-lang/python-3.9.16:3.9 ) python_single_target_python3_10? ( >=dev-lang/python-3.10.9:3.10 ) python_single_target_python3_11? ( >=dev-lang/python-3.11.1:3.11 )
+BDEPEND=python_single_target_python3_9? ( >=dev-lang/python-3.9.16:3.9 ) python_single_target_python3_10? ( >=dev-lang/python-3.10.9:3.10 ) python_single_target_python3_11? ( >=dev-lang/python-3.11.1:3.11 )
 DEFINED_PHASES=configure prepare setup
-DEPEND=dev-lang/perl python_single_target_python3_8? ( dev-python/matplotlib[python_targets_python3_8(-)] ) python_single_target_python3_9? ( dev-python/matplotlib[python_targets_python3_9(-)] ) python_single_target_python3_10? ( dev-python/matplotlib[python_targets_python3_10(-)] ) python_single_target_python3_11? ( dev-python/matplotlib[python_targets_python3_11(-)] ) =sci-libs/htslib-1.16*:= sys-libs/zlib python_single_target_python3_8? ( >=dev-lang/python-3.8.16:3.8 ) python_single_target_python3_9? ( >=dev-lang/python-3.9.16:3.9 ) python_single_target_python3_10? ( >=dev-lang/python-3.10.9:3.10 ) python_single_target_python3_11? ( >=dev-lang/python-3.11.1:3.11 )
+DEPEND=dev-lang/perl python_single_target_python3_9? ( dev-python/matplotlib[python_targets_python3_9(-)] ) python_single_target_python3_10? ( dev-python/matplotlib[python_targets_python3_10(-)] ) python_single_target_python3_11? ( dev-python/matplotlib[python_targets_python3_11(-)] ) =sci-libs/htslib-1.16*:= sys-libs/zlib python_single_target_python3_9? ( >=dev-lang/python-3.9.16:3.9 ) python_single_target_python3_10? ( >=dev-lang/python-3.10.9:3.10 ) python_single_target_python3_11? ( >=dev-lang/python-3.11.1:3.11 )
 DESCRIPTION=Utilities for variant calling and manipulating VCF and BCF files
 EAPI=8
 HOMEPAGE=http://www.htslib.org
 INHERIT=python-single-r1
-IUSE=python_single_target_python3_8 python_single_target_python3_9 python_single_target_python3_10 python_single_target_python3_11
+IUSE=python_single_target_python3_9 python_single_target_python3_10 python_single_target_python3_11
 KEYWORDS=~amd64 ~x86
 LICENSE=MIT
-RDEPEND=dev-lang/perl python_single_target_python3_8? ( dev-python/matplotlib[python_targets_python3_8(-)] ) python_single_target_python3_9? ( dev-python/matplotlib[python_targets_python3_9(-)] ) python_single_target_python3_10? ( dev-python/matplotlib[python_targets_python3_10(-)] ) python_single_target_python3_11? ( dev-python/matplotlib[python_targets_python3_11(-)] ) =sci-libs/htslib-1.16*:= sys-libs/zlib python_single_target_python3_8? ( >=dev-lang/python-3.8.16:3.8 ) python_single_target_python3_9? ( >=dev-lang/python-3.9.16:3.9 ) python_single_target_python3_10? ( >=dev-lang/python-3.10.9:3.10 ) python_single_target_python3_11? ( >=dev-lang/python-3.11.1:3.11 )
-REQUIRED_USE=^^ ( python_single_target_python3_8 python_single_target_python3_9 python_single_target_python3_10 python_single_target_python3_11 )
+RDEPEND=dev-lang/perl python_single_target_python3_9? ( dev-python/matplotlib[python_targets_python3_9(-)] ) python_single_target_python3_10? ( dev-python/matplotlib[python_targets_python3_10(-)] ) python_single_target_python3_11? ( dev-python/matplotlib[python_targets_python3_11(-)] ) =sci-libs/htslib-1.16*:= sys-libs/zlib python_single_target_python3_9? ( >=dev-lang/python-3.9.16:3.9 ) python_single_target_python3_10? ( >=dev-lang/python-3.10.9:3.10 ) python_single_target_python3_11? ( >=dev-lang/python-3.11.1:3.11 )
+REQUIRED_USE=^^ ( python_single_target_python3_9 python_single_target_python3_10 python_single_target_python3_11 )
 SLOT=0
 SRC_URI=https://github.com/samtools/bcftools/releases/download/1.16/bcftools-1.16.tar.bz2
-_eclasses_=multilib	5ca4e49abed8e3a2f7b56920eadee157	multiprocessing	b4e253ab22cef7b1085e9b67c7a3b730	python-single-r1	75118e916668a74c660a13b0ecb22562	python-utils-r1	7870d60e8b98856ef02d33397fd5ec0f	toolchain-funcs	ec8bbc28394c7305b43ea07164bd8f5f
-_md5_=6db47fe6dd9b7f6dae282c829dd08dbd
+_eclasses_=multilib	5ca4e49abed8e3a2f7b56920eadee157	multiprocessing	b4e253ab22cef7b1085e9b67c7a3b730	python-single-r1	75118e916668a74c660a13b0ecb22562	python-utils-r1	a1a985ddd8795a8634b4b7f820b93143	toolchain-funcs	ec8bbc28394c7305b43ea07164bd8f5f
+_md5_=5271780ace94107aae357a985f191e14
diff --git a/metadata/md5-cache/sci-biology/bedtools-2.30.0 b/metadata/md5-cache/sci-biology/bedtools-2.30.0
index 059dc8a4cf88..5c7a21ad3186 100644
--- a/metadata/md5-cache/sci-biology/bedtools-2.30.0
+++ b/metadata/md5-cache/sci-biology/bedtools-2.30.0
@@ -1,4 +1,4 @@
-BDEPEND=|| ( >=dev-lang/python-3.11.1:3.11 >=dev-lang/python-3.10.9:3.10 >=dev-lang/python-3.9.16:3.9 >=dev-lang/python-3.8.16:3.8 ) test? ( >=sci-biology/samtools-1.10:0 )
+BDEPEND=|| ( >=dev-lang/python-3.11.1:3.11 >=dev-lang/python-3.10.9:3.10 >=dev-lang/python-3.9.16:3.9 ) test? ( >=sci-biology/samtools-1.10:0 )
 DEFINED_PHASES=configure install setup
 DEPEND=app-arch/bzip2 app-arch/xz-utils sys-libs/zlib
 DESCRIPTION=Tools for manipulation and analysis of BED, GFF/GTF, VCF, SAM/BAM file formats
@@ -12,5 +12,5 @@ RDEPEND=app-arch/bzip2 app-arch/xz-utils sys-libs/zlib
 RESTRICT=!test? ( test )
 SLOT=0
 SRC_URI=https://github.com/arq5x/bedtools2/releases/download/v2.30.0/bedtools-2.30.0.tar.gz
-_eclasses_=multilib	5ca4e49abed8e3a2f7b56920eadee157	multiprocessing	b4e253ab22cef7b1085e9b67c7a3b730	python-any-r1	d2955aaac8daaaa69fcc6dc93ed19f29	python-utils-r1	7870d60e8b98856ef02d33397fd5ec0f	toolchain-funcs	ec8bbc28394c7305b43ea07164bd8f5f
-_md5_=5f18ddd41275559b1783fee4a2405f1f
+_eclasses_=multilib	5ca4e49abed8e3a2f7b56920eadee157	multiprocessing	b4e253ab22cef7b1085e9b67c7a3b730	python-any-r1	d2955aaac8daaaa69fcc6dc93ed19f29	python-utils-r1	a1a985ddd8795a8634b4b7f820b93143	toolchain-funcs	ec8bbc28394c7305b43ea07164bd8f5f
+_md5_=a8923ba46d6cb3a1840954c1b014568c
diff --git a/metadata/md5-cache/sci-biology/biopandas-0.2.7 b/metadata/md5-cache/sci-biology/biopandas-0.2.7
index 721cf16f2c80..bde7ee1b7687 100644
--- a/metadata/md5-cache/sci-biology/biopandas-0.2.7
+++ b/metadata/md5-cache/sci-biology/biopandas-0.2.7
@@ -1,16 +1,16 @@
-BDEPEND=test? ( dev-python/numpy[python_targets_python3_8(-)?,python_targets_python3_9(-)?,python_targets_python3_10(-)?] dev-python/pandas[python_targets_python3_8(-)?,python_targets_python3_9(-)?,python_targets_python3_10(-)?] dev-python/scipy[python_targets_python3_8(-)?,python_targets_python3_9(-)?,python_targets_python3_10(-)?] >=dev-python/nose-1.3.7_p20221026[python_targets_python3_8(-)?,python_targets_python3_9(-)?,python_targets_python3_10(-)?] ) python_targets_python3_8? ( >=dev-lang/python-3.8.16:3.8 ) python_targets_python3_9? ( >=dev-lang/python-3.9.16:3.9 ) python_targets_python3_10? ( >=dev-lang/python-3.10.9:3.10 ) >=dev-python/setuptools-65.5.1[python_targets_python3_8(-)?,python_targets_python3_9(-)?,python_targets_python3_10(-)?]
+BDEPEND=test? ( dev-python/numpy[python_targets_python3_9(-)?,python_targets_python3_10(-)?] dev-python/pandas[python_targets_python3_9(-)?,python_targets_python3_10(-)?] dev-python/scipy[python_targets_python3_9(-)?,python_targets_python3_10(-)?] >=dev-python/nose-1.3.7_p20221026[python_targets_python3_9(-)?,python_targets_python3_10(-)?] ) python_targets_python3_9? ( >=dev-lang/python-3.9.16:3.9 ) python_targets_python3_10? ( >=dev-lang/python-3.10.9:3.10 ) >=dev-python/setuptools-65.5.1[python_targets_python3_9(-)?,python_targets_python3_10(-)?]
 DEFINED_PHASES=compile configure install prepare test
 DESCRIPTION=Molecular Structures in Pandas DataFrames
 EAPI=8
 HOMEPAGE=https://rasbt.github.io/biopandas/ https://github.com/rasbt/biopandas https://pypi.org/project/BioPandas/
 INHERIT=distutils-r1
-IUSE=test test python_targets_python3_8 python_targets_python3_9 python_targets_python3_10
+IUSE=test test python_targets_python3_9 python_targets_python3_10
 KEYWORDS=~amd64 ~x86 ~amd64-linux ~x86-linux
 LICENSE=BSD
-RDEPEND=dev-python/numpy[python_targets_python3_8(-)?,python_targets_python3_9(-)?,python_targets_python3_10(-)?] dev-python/pandas[python_targets_python3_8(-)?,python_targets_python3_9(-)?,python_targets_python3_10(-)?] dev-python/scipy[python_targets_python3_8(-)?,python_targets_python3_9(-)?,python_targets_python3_10(-)?] python_targets_python3_8? ( >=dev-lang/python-3.8.16:3.8 ) python_targets_python3_9? ( >=dev-lang/python-3.9.16:3.9 ) python_targets_python3_10? ( >=dev-lang/python-3.10.9:3.10 )
-REQUIRED_USE=|| ( python_targets_python3_8 python_targets_python3_9 python_targets_python3_10 )
+RDEPEND=dev-python/numpy[python_targets_python3_9(-)?,python_targets_python3_10(-)?] dev-python/pandas[python_targets_python3_9(-)?,python_targets_python3_10(-)?] dev-python/scipy[python_targets_python3_9(-)?,python_targets_python3_10(-)?] python_targets_python3_9? ( >=dev-lang/python-3.9.16:3.9 ) python_targets_python3_10? ( >=dev-lang/python-3.10.9:3.10 )
+REQUIRED_USE=|| ( python_targets_python3_9 python_targets_python3_10 )
 RESTRICT=!test? ( test ) !test? ( test )
 SLOT=0
 SRC_URI=mirror://pypi/B/BioPandas/biopandas-0.2.7.tar.gz
-_eclasses_=distutils-r1	dcd5f48510105eb95e550ab968147365	multibuild	bddcb51b74f4a76724ff7cf8e7388869	multilib	5ca4e49abed8e3a2f7b56920eadee157	multiprocessing	b4e253ab22cef7b1085e9b67c7a3b730	ninja-utils	38c85b725d0467e51954ea921b6c104b	out-of-source-utils	1a9007554652a6e627edbccb3c25a439	python-r1	666be58f658d6b32affe30f80e39a49e	python-utils-r1	7870d60e8b98856ef02d33397fd5ec0f	toolchain-funcs	ec8bbc28394c7305b43ea07164bd8f5f
-_md5_=493935812e002415b6fce30c9e9dc8f8
+_eclasses_=distutils-r1	dcd5f48510105eb95e550ab968147365	multibuild	bddcb51b74f4a76724ff7cf8e7388869	multilib	5ca4e49abed8e3a2f7b56920eadee157	multiprocessing	b4e253ab22cef7b1085e9b67c7a3b730	ninja-utils	38c85b725d0467e51954ea921b6c104b	out-of-source-utils	1a9007554652a6e627edbccb3c25a439	python-r1	666be58f658d6b32affe30f80e39a49e	python-utils-r1	a1a985ddd8795a8634b4b7f820b93143	toolchain-funcs	ec8bbc28394c7305b43ea07164bd8f5f
+_md5_=90f9103bd8f00cfb13d8821454edb4b8
diff --git a/metadata/md5-cache/sci-biology/biopython-1.79 b/metadata/md5-cache/sci-biology/biopython-1.79
index 1f74f80535b3..721df3f77937 100644
--- a/metadata/md5-cache/sci-biology/biopython-1.79
+++ b/metadata/md5-cache/sci-biology/biopython-1.79
@@ -1,16 +1,16 @@
-BDEPEND=sys-devel/flex python_targets_python3_8? ( >=dev-lang/python-3.8.16:3.8 ) python_targets_python3_9? ( >=dev-lang/python-3.9.16:3.9 ) python_targets_python3_10? ( >=dev-lang/python-3.10.9:3.10 ) >=dev-python/setuptools-65.5.1[python_targets_python3_8(-)?,python_targets_python3_9(-)?,python_targets_python3_10(-)?]
+BDEPEND=sys-devel/flex python_targets_python3_9? ( >=dev-lang/python-3.9.16:3.9 ) python_targets_python3_10? ( >=dev-lang/python-3.10.9:3.10 ) >=dev-python/setuptools-65.5.1[python_targets_python3_9(-)?,python_targets_python3_10(-)?]
 DEFINED_PHASES=compile configure install postinst prepare test
-DEPEND=dev-python/matplotlib[python_targets_python3_8(-)?,python_targets_python3_9(-)?,python_targets_python3_10(-)?] dev-python/networkx[python_targets_python3_8(-)?,python_targets_python3_9(-)?,python_targets_python3_10(-)?] dev-python/numpy[python_targets_python3_8(-)?,python_targets_python3_9(-)?,python_targets_python3_10(-)?] dev-python/rdflib[python_targets_python3_8(-)?,python_targets_python3_9(-)?,python_targets_python3_10(-)?] dev-python/pygraphviz[python_targets_python3_8(-)?,python_targets_python3_9(-)?,python_targets_python3_10(-)?] >=dev-python/reportlab-3.5.13-r1[python_targets_python3_8(-)?,python_targets_python3_9(-)?,python_targets_python3_10(-)?] dev-python/pydot[python_targets_python3_8(-)?,python_targets_python3_9(-)?,python_targets_python3_10(-)?]
+DEPEND=dev-python/matplotlib[python_targets_python3_9(-)?,python_targets_python3_10(-)?] dev-python/networkx[python_targets_python3_9(-)?,python_targets_python3_10(-)?] dev-python/numpy[python_targets_python3_9(-)?,python_targets_python3_10(-)?] dev-python/rdflib[python_targets_python3_9(-)?,python_targets_python3_10(-)?] dev-python/pygraphviz[python_targets_python3_9(-)?,python_targets_python3_10(-)?] >=dev-python/reportlab-3.5.13-r1[python_targets_python3_9(-)?,python_targets_python3_10(-)?] dev-python/pydot[python_targets_python3_9(-)?,python_targets_python3_10(-)?]
 DESCRIPTION=Python modules for computational molecular biology
 EAPI=8
 HOMEPAGE=https://www.biopython.org/ https://pypi.org/project/biopython/
 INHERIT=distutils-r1 optfeature
-IUSE=python_targets_python3_8 python_targets_python3_9 python_targets_python3_10
+IUSE=python_targets_python3_9 python_targets_python3_10
 KEYWORDS=~amd64 ~x86 ~amd64-linux ~x86-linux
 LICENSE=HPND
-RDEPEND=dev-python/matplotlib[python_targets_python3_8(-)?,python_targets_python3_9(-)?,python_targets_python3_10(-)?] dev-python/networkx[python_targets_python3_8(-)?,python_targets_python3_9(-)?,python_targets_python3_10(-)?] dev-python/numpy[python_targets_python3_8(-)?,python_targets_python3_9(-)?,python_targets_python3_10(-)?] dev-python/rdflib[python_targets_python3_8(-)?,python_targets_python3_9(-)?,python_targets_python3_10(-)?] dev-python/pygraphviz[python_targets_python3_8(-)?,python_targets_python3_9(-)?,python_targets_python3_10(-)?] >=dev-python/reportlab-3.5.13-r1[python_targets_python3_8(-)?,python_targets_python3_9(-)?,python_targets_python3_10(-)?] dev-python/pydot[python_targets_python3_8(-)?,python_targets_python3_9(-)?,python_targets_python3_10(-)?] python_targets_python3_8? ( >=dev-lang/python-3.8.16:3.8 ) python_targets_python3_9? ( >=dev-lang/python-3.9.16:3.9 ) python_targets_python3_10? ( >=dev-lang/python-3.10.9:3.10 )
-REQUIRED_USE=|| ( python_targets_python3_8 python_targets_python3_9 python_targets_python3_10 )
+RDEPEND=dev-python/matplotlib[python_targets_python3_9(-)?,python_targets_python3_10(-)?] dev-python/networkx[python_targets_python3_9(-)?,python_targets_python3_10(-)?] dev-python/numpy[python_targets_python3_9(-)?,python_targets_python3_10(-)?] dev-python/rdflib[python_targets_python3_9(-)?,python_targets_python3_10(-)?] dev-python/pygraphviz[python_targets_python3_9(-)?,python_targets_python3_10(-)?] >=dev-python/reportlab-3.5.13-r1[python_targets_python3_9(-)?,python_targets_python3_10(-)?] dev-python/pydot[python_targets_python3_9(-)?,python_targets_python3_10(-)?] python_targets_python3_9? ( >=dev-lang/python-3.9.16:3.9 ) python_targets_python3_10? ( >=dev-lang/python-3.10.9:3.10 )
+REQUIRED_USE=|| ( python_targets_python3_9 python_targets_python3_10 )
 SLOT=0
 SRC_URI=mirror://pypi/b/biopython/biopython-1.79.tar.gz
-_eclasses_=distutils-r1	dcd5f48510105eb95e550ab968147365	multibuild	bddcb51b74f4a76724ff7cf8e7388869	multilib	5ca4e49abed8e3a2f7b56920eadee157	multiprocessing	b4e253ab22cef7b1085e9b67c7a3b730	ninja-utils	38c85b725d0467e51954ea921b6c104b	optfeature	1a2157392a869265b2afcb63a26c12ac	out-of-source-utils	1a9007554652a6e627edbccb3c25a439	python-r1	666be58f658d6b32affe30f80e39a49e	python-utils-r1	7870d60e8b98856ef02d33397fd5ec0f	toolchain-funcs	ec8bbc28394c7305b43ea07164bd8f5f
-_md5_=89d2124a2c9f76eda9c399f23c96a8b8
+_eclasses_=distutils-r1	dcd5f48510105eb95e550ab968147365	multibuild	bddcb51b74f4a76724ff7cf8e7388869	multilib	5ca4e49abed8e3a2f7b56920eadee157	multiprocessing	b4e253ab22cef7b1085e9b67c7a3b730	ninja-utils	38c85b725d0467e51954ea921b6c104b	optfeature	1a2157392a869265b2afcb63a26c12ac	out-of-source-utils	1a9007554652a6e627edbccb3c25a439	python-r1	666be58f658d6b32affe30f80e39a49e	python-utils-r1	a1a985ddd8795a8634b4b7f820b93143	toolchain-funcs	ec8bbc28394c7305b43ea07164bd8f5f
+_md5_=6074a70b897177a12216367dcd1352a1
diff --git a/metadata/md5-cache/sci-biology/bowtie-2.4.4 b/metadata/md5-cache/sci-biology/bowtie-2.4.4
index 1ad723653bc9..f9458d456ab1 100644
--- a/metadata/md5-cache/sci-biology/bowtie-2.4.4
+++ b/metadata/md5-cache/sci-biology/bowtie-2.4.4
@@ -1,16 +1,16 @@
 BDEPEND=app-arch/unzip
 DEFINED_PHASES=compile install setup
-DEPEND=python_single_target_python3_8? ( >=dev-lang/python-3.8.16:3.8 ) python_single_target_python3_9? ( >=dev-lang/python-3.9.16:3.9 ) python_single_target_python3_10? ( >=dev-lang/python-3.10.9:3.10 ) dev-lang/perl sys-libs/zlib
+DEPEND=python_single_target_python3_9? ( >=dev-lang/python-3.9.16:3.9 ) python_single_target_python3_10? ( >=dev-lang/python-3.10.9:3.10 ) dev-lang/perl sys-libs/zlib
 DESCRIPTION=Popular short read aligner for Next-generation sequencing data
 EAPI=8
 HOMEPAGE=http://bowtie-bio.sourceforge.net/bowtie2/
 INHERIT=python-single-r1 toolchain-funcs
-IUSE=cpu_flags_x86_sse2 examples python_single_target_python3_8 python_single_target_python3_9 python_single_target_python3_10
+IUSE=cpu_flags_x86_sse2 examples python_single_target_python3_9 python_single_target_python3_10
 KEYWORDS=~amd64 ~x86
 LICENSE=GPL-3
-RDEPEND=python_single_target_python3_8? ( >=dev-lang/python-3.8.16:3.8 ) python_single_target_python3_9? ( >=dev-lang/python-3.9.16:3.9 ) python_single_target_python3_10? ( >=dev-lang/python-3.10.9:3.10 ) dev-lang/perl sys-libs/zlib
-REQUIRED_USE=cpu_flags_x86_sse2 ^^ ( python_single_target_python3_8 python_single_target_python3_9 python_single_target_python3_10 )
+RDEPEND=python_single_target_python3_9? ( >=dev-lang/python-3.9.16:3.9 ) python_single_target_python3_10? ( >=dev-lang/python-3.10.9:3.10 ) dev-lang/perl sys-libs/zlib
+REQUIRED_USE=cpu_flags_x86_sse2 ^^ ( python_single_target_python3_9 python_single_target_python3_10 )
 SLOT=2
 SRC_URI=mirror://sourceforge/project/bowtie-bio/bowtie2/2.4.4/bowtie2-2.4.4-source.zip
-_eclasses_=multilib	5ca4e49abed8e3a2f7b56920eadee157	multiprocessing	b4e253ab22cef7b1085e9b67c7a3b730	python-single-r1	75118e916668a74c660a13b0ecb22562	python-utils-r1	7870d60e8b98856ef02d33397fd5ec0f	toolchain-funcs	ec8bbc28394c7305b43ea07164bd8f5f
-_md5_=a169406c93e64d9cae6cbb8ad262f62b
+_eclasses_=multilib	5ca4e49abed8e3a2f7b56920eadee157	multiprocessing	b4e253ab22cef7b1085e9b67c7a3b730	python-single-r1	75118e916668a74c660a13b0ecb22562	python-utils-r1	a1a985ddd8795a8634b4b7f820b93143	toolchain-funcs	ec8bbc28394c7305b43ea07164bd8f5f
+_md5_=7e782380091eb080dc11ed573335cbf2
diff --git a/metadata/md5-cache/sci-biology/pysam-0.19.1 b/metadata/md5-cache/sci-biology/pysam-0.19.1
index e37badaa004f..85477d5a75ce 100644
--- a/metadata/md5-cache/sci-biology/pysam-0.19.1
+++ b/metadata/md5-cache/sci-biology/pysam-0.19.1
@@ -1,17 +1,17 @@
-BDEPEND=test? ( =sci-biology/bcftools-1.15.1* =sci-biology/samtools-1.15.1* ) test? ( =sci-libs/htslib-1.15.1*:= >=dev-python/pytest-7.1.3[python_targets_python3_8(-)?,python_targets_python3_9(-)?,python_targets_python3_10(-)?,python_targets_python3_11(-)?] ) python_targets_python3_8? ( >=dev-lang/python-3.8.16:3.8 ) python_targets_python3_9? ( >=dev-lang/python-3.9.16:3.9 ) python_targets_python3_10? ( >=dev-lang/python-3.10.9:3.10 ) python_targets_python3_11? ( >=dev-lang/python-3.11.1:3.11 ) >=dev-python/setuptools-65.5.1[python_targets_python3_8(-)?,python_targets_python3_9(-)?,python_targets_python3_10(-)?,python_targets_python3_11(-)?]
+BDEPEND=test? ( =sci-biology/bcftools-1.15.1* =sci-biology/samtools-1.15.1* ) test? ( =sci-libs/htslib-1.15.1*:= >=dev-python/pytest-7.1.3[python_targets_python3_9(-)?,python_targets_python3_10(-)?,python_targets_python3_11(-)?] ) python_targets_python3_9? ( >=dev-lang/python-3.9.16:3.9 ) python_targets_python3_10? ( >=dev-lang/python-3.10.9:3.10 ) python_targets_python3_11? ( >=dev-lang/python-3.11.1:3.11 ) >=dev-python/setuptools-65.5.1[python_targets_python3_9(-)?,python_targets_python3_10(-)?,python_targets_python3_11(-)?]
 DEFINED_PHASES=compile configure install prepare test
-DEPEND==sci-libs/htslib-1.15.1*:= dev-python/cython[python_targets_python3_8(-)?,python_targets_python3_9(-)?,python_targets_python3_10(-)?,python_targets_python3_11(-)?] dev-python/setuptools[python_targets_python3_8(-)?,python_targets_python3_9(-)?,python_targets_python3_10(-)?,python_targets_python3_11(-)?]
+DEPEND==sci-libs/htslib-1.15.1*:= dev-python/cython[python_targets_python3_9(-)?,python_targets_python3_10(-)?,python_targets_python3_11(-)?] dev-python/setuptools[python_targets_python3_9(-)?,python_targets_python3_10(-)?,python_targets_python3_11(-)?]
 DESCRIPTION=Python interface for the SAM/BAM sequence alignment and mapping format
 EAPI=8
 HOMEPAGE=https://github.com/pysam-developers/pysam https://pypi.org/project/pysam/
 INHERIT=distutils-r1
-IUSE=test python_targets_python3_8 python_targets_python3_9 python_targets_python3_10 python_targets_python3_11
+IUSE=test python_targets_python3_9 python_targets_python3_10 python_targets_python3_11
 KEYWORDS=~amd64 ~x86
 LICENSE=MIT
-RDEPEND==sci-libs/htslib-1.15.1*:= python_targets_python3_8? ( >=dev-lang/python-3.8.16:3.8 ) python_targets_python3_9? ( >=dev-lang/python-3.9.16:3.9 ) python_targets_python3_10? ( >=dev-lang/python-3.10.9:3.10 ) python_targets_python3_11? ( >=dev-lang/python-3.11.1:3.11 )
-REQUIRED_USE=|| ( python_targets_python3_8 python_targets_python3_9 python_targets_python3_10 python_targets_python3_11 )
+RDEPEND==sci-libs/htslib-1.15.1*:= python_targets_python3_9? ( >=dev-lang/python-3.9.16:3.9 ) python_targets_python3_10? ( >=dev-lang/python-3.10.9:3.10 ) python_targets_python3_11? ( >=dev-lang/python-3.11.1:3.11 )
+REQUIRED_USE=|| ( python_targets_python3_9 python_targets_python3_10 python_targets_python3_11 )
 RESTRICT=!test? ( test )
 SLOT=0
 SRC_URI=https://github.com/pysam-developers/pysam/archive/v0.19.1.tar.gz -> pysam-0.19.1.gh.tar.gz
-_eclasses_=distutils-r1	dcd5f48510105eb95e550ab968147365	multibuild	bddcb51b74f4a76724ff7cf8e7388869	multilib	5ca4e49abed8e3a2f7b56920eadee157	multiprocessing	b4e253ab22cef7b1085e9b67c7a3b730	ninja-utils	38c85b725d0467e51954ea921b6c104b	out-of-source-utils	1a9007554652a6e627edbccb3c25a439	python-r1	666be58f658d6b32affe30f80e39a49e	python-utils-r1	7870d60e8b98856ef02d33397fd5ec0f	toolchain-funcs	ec8bbc28394c7305b43ea07164bd8f5f
-_md5_=baed35c86cd8709cd139815786cd17ac
+_eclasses_=distutils-r1	dcd5f48510105eb95e550ab968147365	multibuild	bddcb51b74f4a76724ff7cf8e7388869	multilib	5ca4e49abed8e3a2f7b56920eadee157	multiprocessing	b4e253ab22cef7b1085e9b67c7a3b730	ninja-utils	38c85b725d0467e51954ea921b6c104b	out-of-source-utils	1a9007554652a6e627edbccb3c25a439	python-r1	666be58f658d6b32affe30f80e39a49e	python-utils-r1	a1a985ddd8795a8634b4b7f820b93143	toolchain-funcs	ec8bbc28394c7305b43ea07164bd8f5f
+_md5_=5bd55873aaed892e71220dbfdc6d68a0